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Due to new therapeutic options, patients with newly diagnosed and relapsed multiple myeloma are living longer than they did just one decade ago. Therefore, patients' general health must also be maintained throughout the course of their disease. Proper maintenance of pre-existing or co-morbid conditions can improve quality of life and extend survival.

The following is a description of additional health issues that multiple myeloma patients may face along with the screening recommendations for each.

Cardiovascular

 

* Depending on a patient’s co-morbid conditions, the treatment of hypertension varies. Multiple myeloma patients who are diagnosed with hypertension should discuss the treatments they require with a cardiovascular specialist.

** The U.S. Preventative Services Task Force makes no recommendations for or against routine screening for lipid disorders in men ages 20-35 or in women ages 20 or older who are not at risk for coronary heart disease.

More information and guidelines can be found at:

•    American Heart Association
•    2025 Guidelines by the American College of Cardiology/American Heart Association (ACC/AHA)
•    National Cholesterol Education Program from the National Institutes of Health

Malignancies

Multiple myeloma patients should continue to be screened for other malignancies throughout the course of their disease, especially if they have a genetic predisposition to other cancers. Some patients do develop secondary cancers. Proper screening and preventative measures can treat these malignancies should they develop.

More information and guidelines can be found at:

 

Endocrine Disorders

*Patients receiving treatment for multiple myeloma can have an increased incidence of hyperglycemia (high blood sugar) when dexamethasone is incorporated into their regimen. The incidence of high blood sugar is actually prevalent in all steroid users.

More information and guidelines can be found at:
•    USPSTF guidelines and recommendations for the screening of Type 2 Diabetes.
•    USPSTF guidelines and recommendations for the screening of Thyroid Dysfunction.
 

Sensory Health


More information and guidelines can be found at:
•    National Eye Institute 
•    American Academy of Ophthalmology 
 

Addiction and Substance Abuse

More information and guidelines can be found at:
•    USPSTF guidelines and recommendations for the screening of Alcohol Misuse.
 

Vaccines

Oral Hygiene

More information and guidelines can be found at:


•    American Dental Association’s Oral Health Recommendations
 



The International Myeloma Foundation medical and editorial content team

Comprised of leading medical researchers, hematologists, oncologists, oncology-certified nurses, medical editors, and medical journalists, our team has extensive knowledge of the multiple myeloma treatment and care landscape. 

Additionally, the content on this page is medically reviewed by myeloma physicians and healthcare professionals.  

Last Medical Review: August 7, 2026 

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