An important component of almost all myeloma therapies dexamethasone is a synthetic adrenocortical steroid, also known as glucocorticosteroid or corticosteroid. Dexamethasone is one of the most frequently used medications in the treatment of myeloma (also known as Decadron®, Dexasone®, Diodex®, Hexadrol®, and Maxidex®).