Survival and years of life lost in different age cohorts of patients with multiple myeloma

The purpose of this study is to determine the correlation between age and survival, as well as how many years myeloma patients will lose due to their condition. In the study, 10,549 patients were studied, with 6,996 receiving conventional therapy, and 3,553 patients receiving high-dose therapy with autologous stem-cell transplantation. Results showed that observed survival decreased as patients were older, going “from 6.4 years in patients younger than age 50 to 2.5 years in patients > or = age 80 years.” Risk of death also changed significantly between older and younger age groups once 40 years old or older. Years myeloma patients lose can be significant, ranging from an average of 30 years for patients younger than 40 years old, but only 5 years in patients 80 years or older.


Ludwig H, Bolejack V, Crowley J, Bladé J, Miguel JS, Kyle RA, Rajkumar SV, Shimizu K, Turesson I, Westin J, Sonneveld P, Cavo M, Boccadoro M, Palumbo A, Tosi P, Harousseau JL, Attal M, Barlogie B, Stewart AK, Durie B.

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