The role of vertebral augmentation in multiple myeloma: International Myeloma Working Group Consensus Statement

This statement attempts to explain four aspects of myeloma:

  • 20,000 new American patients are diagnosed every year
  • There are about 100,000 myeloma patients in America due to better forms of treatment that increase survival rates. This statistic is the same throughout Europe.
  • Myeloma is associated with osteolytic or osteopenic bone disease, as seen in 70% of patients.
  • Myeloma is the most common form of cancer in the spine, resulting in vertebral compression fractures (VCFs) that are painful for the 30% of patients it affects.

This summary’s goal is to see how the use of polymethyl methacrylate (PMMA) injection can help relieve the pain caused by VCFs. Not only does the summary state whether PMMA will relieve the pain of VCFs, but the physical benefits the spine will have from PMMA.


Hussein MA, Vrionis FD, Allison R, Berenson J, Berven S, Erdem E, Giralt S, Jagannath S, Kyle RA, LeGrand S, Pflugmacher R, Raje N, Rajkumar SV, Randall RL, Roodman D, Siegel D, Vescio R, Zonder J, Durie BG; International Myeloma Working Group.

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