Genetic predisposition for chemotherapy-induced neuropathy in multiple myeloma

Many cancer patients who undergo chemotherapy experience peripheral neuropathy, which is characterized by numbness, tingling, and/or pain in the hands, feet, legs, and/or arms. In fact, almost every effective regimen for the treatment of multiple myeloma “includes at least one agent that can cause neuropathy.” Neuropathy may even occur prior to therapy due to the disease itself, and “can even occur in the precursor condition, monoclonal gammopathy of undetermined significance.”

Authors: Becker p. et al.

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