Stage Criteria
I

Serum β2 microglobulin < 3.5 mg/l
Serum albumin ≥ 3.5 g/dl
Standard-risk chromosomal abnormalities (CA)
Normal LDH

II Not R-ISS stage I or III
III

Serum β2 microglobulin ≥ 5.5 mg/L and either
High-risk CA by FISH
OR
High LDH



The International Myeloma Foundation medical and editorial content team

Comprised of leading medical researchers, hematologist, oncologists, oncology-certified nurses, medical editors, and medical journalists, our team has extensive knowledge of the multiple myeloma treatment and care landscape. Additionally, Dr. Brian G.M. Durie reviews and approves all medical content on this website.

Last Medical Review: August 1, 2019

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