Stage Criteria
I

Serum β2 microglobulin < 3.5 mg/l
Serum albumin ≥ 3.5 g/dl
Standard-risk chromosomal abnormalities (CA)
Normal LDH

II Not R-ISS stage I or III
III

Serum β2 microglobulin ≥ 5.5 mg/L and either
High-risk CA by FISH
OR
High LDH

Give Where Most Needed

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